Drug Information

Drug General Information
Drug ID
D0UI7U
Former ID
DIB020373
Drug Name
ML315
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532342]
Formula
C18H13Cl2N3O2
InChI
InChI=1S/C18H13Cl2N3O2/c19-13-3-11(4-14(20)6-13)7-22-18-15(8-21-9-23-18)12-1-2-16-17(5-12)25-10-24-16/h1-6,8-9H,7,10H2,(H,21,22,23)
InChIKey
JQSJAVBMIMDUFO-UHFFFAOYSA-N
PubChem Compound ID
46926514
PubChem Substance ID
99431981, 124360160, 124950388, 162067039, 163818262, 174006429, 174484676, 175447791, 249565842
Target and Pathway
Target(s) CDC-like kinase 4 Target Info Inhibitor [532342]
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Target Info Inhibitor [532342]
CDC-like kinase 2 Target Info Inhibitor [532342]
Cdc2-like kinase 1 Target Info Inhibitor [532342]
NetPath Pathway TCR Signaling Pathway
EGFR1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
WikiPathways mRNA Processing
References
Ref 532342Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315. Bioorg Med Chem Lett. 2013 Jun15;23(12):3654-61.
Ref 532342Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315. Bioorg Med Chem Lett. 2013 Jun15;23(12):3654-61.

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