Drug Information

Drug General Information
Drug ID
D0TM0N
Former ID
DIB021115
Drug Name
UCM 765
Synonyms
UCM-765; UCM765
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542842]
Formula
C17H20N2O2
InChI
InChI=1S/C17H20N2O2/c1-14(20)18-12-13-19(15-6-4-3-5-7-15)16-8-10-17(21-2)11-9-16/h3-11H,12-13H2,1-2H3,(H,18,20)
InChIKey
PWTCGLHUMIIRML-UHFFFAOYSA-N
PubChem Compound ID
24749950
PubChem Substance ID
49652124, 56165376, 103541936, 229420378, 248495470, 249565606
Target and Pathway
Target(s) Melatonin receptor Target Info Agonist [529190]
KEGG Pathway Neuroactive ligand-receptor interaction
Circadian entrainment
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 542842(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7923).
Ref 529190N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands. J Med Chem. 2007 Dec 27;50(26):6618-26. Epub 2007 Dec 6.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.