Drug Information

Drug General Information
Drug ID
D0T3UP
Former ID
DNC004184
Drug Name
1,3-Dihydro-naphtho[2,3-d]imidazol-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528087]
Formula
C11H8N2O
Canonical SMILES
C1=CC=C2C=C3C(=CC2=C1)NC(=O)N3
InChI
1S/C11H8N2O/c14-11-12-9-5-7-3-1-2-4-8(7)6-10(9)13-11/h1-6H,(H2,12,13,14)
InChIKey
HUOPXZLFTBYAML-UHFFFAOYSA-N
PubChem Compound ID
13724742
Target and Pathway
Target(s) CGMP-inhibited 3',5'-cyclic phosphodiesterase A Target Info Inhibitor [528087]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
cAMP signaling pathway
Morphine addiction
Reactome cGMP effects
G alpha (s) signalling events
WikiPathways miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 528087J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.
Ref 528087J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.