Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0T2VH
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| Former ID |
DNC009403
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| Drug Name |
N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)sulfamide
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [529794] | ||
| Formula |
C6H12N4O2S2
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| Canonical SMILES |
CC(C)(C)C1=NN=C(S1)NS(=O)(=O)N
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| InChI |
1S/C6H12N4O2S2/c1-6(2,3)4-8-9-5(13-4)10-14(7,11)12/h1-3H3,(H,9,10)(H2,7,11,12)
|
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| InChIKey |
JJBJNTIFYMQMKH-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Carbonic anhydrase II | Target Info | Inhibitor | [529794] | |
| Carbonic anhydrase IV | Target Info | Inhibitor | [529794] | ||
| Carbonic anhydrase | Target Info | Inhibitor | [529794] | ||
| Carbonic anhydrase I | Target Info | Inhibitor | [529794] | ||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| EGFR1 Signaling Pathway | |||||
| Pathway Interaction Database | C-MYB transcription factor network | ||||
| PathWhiz Pathway | Gastric Acid Production | ||||
| References | |||||
| Ref 529794 | Bioorg Med Chem Lett. 2008 Dec 15;18(24):6332-5. Epub 2008 Nov 1.Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV. | ||||
| Ref 529794 | Bioorg Med Chem Lett. 2008 Dec 15;18(24):6332-5. Epub 2008 Nov 1.Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV. | ||||
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