Drug Information

Drug General Information
Drug ID
D0SI7S
Former ID
DNC009076
Drug Name
5,6,7,8-tetrahydroanthracene-1,4-dione
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529817]
Formula
C14H12O2
Canonical SMILES
C1CCC2=C(C1)C=C3C(=O)C=CC(=O)C3=C2
InChI
1S/C14H12O2/c15-13-5-6-14(16)12-8-10-4-2-1-3-9(10)7-11(12)13/h5-8H,1-4H2
InChIKey
DWXLNXHEUIUNRF-UHFFFAOYSA-N
PubChem Compound ID
44582382
Target and Pathway
Target(s) M-phase inducer phosphatase 2 Target Info Inhibitor [529817]
KEGG Pathway MAPK signaling pathway
Cell cycle
Progesterone-mediated oocyte maturation
MicroRNAs in cancer
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Wnt Signaling Pathway
Pathway Interaction Database PLK1 signaling events
FOXM1 transcription factor network
p38 signaling mediated by MAPKAP kinases
Aurora A signaling
Reactome Cyclin B2 mediated events
Cyclin A/B1 associated events during G2/M transition
Cyclin A:Cdk2-associated events at S phase entry
WikiPathways Senescence and Autophagy in Cancer
MAPK Signaling Pathway
Retinoblastoma (RB) in Cancer
Prostate Cancer
Integrated Breast Cancer Pathway
Integrated Cancer pathway
Mitotic G2-G2/M phases
Cell Cycle
References
Ref 529817Bioorg Med Chem. 2009 Mar 15;17(6):2276-81. Epub 2008 Nov 8.Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases.
Ref 529817Bioorg Med Chem. 2009 Mar 15;17(6):2276-81. Epub 2008 Nov 8.Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases.

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