Drug Information

Drug General Information
Drug ID
D0S6SQ
Former ID
DIB014666
Drug Name
Odelepran
Synonyms
Odelepran hydrochloride; LY2196044 HCl; LY-2196044; OpRA (alcohol dependence), Eli Lilly; OpRA II (alcoholism), Eli Lilly; Opioid receptor antagonist (alcoholism), Eli Lilly
Drug Type
Small molecular drug
Indication Alcohol use disorders [ICD9: 303; ICD10:F10.2] Phase 2 [522511]
Company
Eli Lilly & Co
Formula
C20H24FN3O3
Canonical SMILES
C(CNCc1cc(c(cc1)Oc1ncc(cc1)C(=O)N)F)C1CCOCC1
PubChem Compound ID
10457387
Target and Pathway
Target(s) Opioid receptor Target Info Antagonist [532470]
References
Ref 522511ClinicalTrials.gov (NCT00804570) A Study for the Treatment of Alcohol Dependence.. U.S. National Institutes of Health.
Ref 532470A phase 2, placebo-controlled study of the opioid receptor antagonist LY2196044 for the treatment of alcohol dependence. Alcohol Clin Exp Res. 2014 Feb;38(2):511-20.

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