Drug Information

Drug General Information
Drug ID
D0S4XR
Former ID
DNC009433
Drug Name
1-(3-(benzyloxy)-2-methylphenyl)piperazine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530058]
Formula
C18H22N2O
Canonical SMILES
CC1=C(C=CC=C1OCC2=CC=CC=C2)N3CCNCC3
InChI
1S/C18H22N2O/c1-15-17(20-12-10-19-11-13-20)8-5-9-18(15)21-14-16-6-3-2-4-7-16/h2-9,19H,10-14H2,1H3
InChIKey
LLKMJMQVKKJDAT-UHFFFAOYSA-N
PubChem Compound ID
25263303
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Inhibitor [530058]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 530058Bioorg Med Chem Lett. 2009 May 1;19(9):2409-12. Epub 2009 Mar 25.Synthesis and SAR of tolylamine 5-HT6 antagonists.
Ref 530058Bioorg Med Chem Lett. 2009 May 1;19(9):2409-12. Epub 2009 Mar 25.Synthesis and SAR of tolylamine 5-HT6 antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.