Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0S0XD
|
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| Former ID |
DIB019456
|
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| Drug Name |
compound 35
|
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| Drug Type |
Small molecular drug
|
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| Formula |
C20H14Cl2N6O2S
|
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| InChI |
InChI=1S/C20H14Cl2N6O2S/c1-10(29)26-20-25-9-17(31-20)14-7-15(18-12(21)5-11(30-2)6-13(18)22)28-19(27-14)16-8-23-3-4-24-16/h3-9H,1-2H3,(H,25,26,29)
|
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| InChIKey |
XACSASLXEAYEEO-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | testis-specific kinase 2 | Target Info | Inhibitor | [532008] | |
| LIM domain kinase 1 | Target Info | Inhibitor | [532008] | ||
| LIM domain kinase 2 | Target Info | Inhibitor | [532008] | ||
| testis-specific kinase 1 | Target Info | Inhibitor | [532008] | ||
| References | |||||
| Ref 526087 | Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells. J Biol Chem. 2001 Aug 17;276(33):31449-58. Epub2001 Jun 19. | ||||
| Ref 532008 | Modulation of cofilin phosphorylation by inhibition of the Lim family kinases. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5995-8. | ||||
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