Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0R8KA
|
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| Former ID |
DIB020780
|
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| Drug Name |
pyrrolopyrimidine 48
|
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| Drug Type |
Small molecular drug
|
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| Formula |
C23H23N5O
|
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| InChI |
InChI=1S/C23H23N5O/c1-2-6-18(7-3-1)16-28-15-11-20-22(28)25-17-26-23(20)29-19-9-13-27(14-10-19)21-8-4-5-12-24-21/h1-8,11-12,15,17,19H,9-10,13-14,16H2
|
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| InChIKey |
ZMRCFNOIVYNNGH-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Voltage-gated sodium channel subunit alpha Nav1.7 | Target Info | Blocker (channel blocker) | [531793] | |
| Reactome | Interaction between L1 and Ankyrins | ||||
| References | |||||
| Ref 531793 | Discovery and hit-to-lead optimization of pyrrolopyrimidines as potent, state-dependent Na(v)1.7 antagonists. Bioorg Med Chem Lett. 2012 Mar 1;22(5):2052-62. | ||||
| Ref 541066 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5731). | ||||
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