Drug Information

Drug General Information
Drug ID
D0R3HX
Former ID
DIB011917
Drug Name
RB-6145
Synonyms
PD-144872
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Discontinued in Phase 1 [545213]
Company
BTG plc
Formula
C8H14Br2N4O3
Canonical SMILES
c1([N+](=O)[O-])n(ccn1)CC(O)CNCCBr.Br
PubChem Compound ID
125377
Target and Pathway
Target(s) Human DNA Target Info Binder [544038]
References
Ref 545213Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002473)
Ref 544038Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. II. RSU 1069.. Br J Cancer. 1995 March; 71(3): 537-542.

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