Drug Information

Drug General Information
Drug ID
D0R1ZD
Former ID
DIB019963
Drug Name
GSK575594A
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540939]
Formula
C24H23F2N3O3S
InChI
InChI=1S/C24H23F2N3O3S/c1-33(31,32)19-7-8-20(16-2-4-17(25)5-3-16)21(15-19)24(30)29-12-10-28(11-13-29)23-9-6-18(27)14-22(23)26/h2-9,14-15H,10-13,27H2,1H3
InChIKey
DAPKZHQMEQRNPY-UHFFFAOYSA-N
PubChem Compound ID
59822766
PubChem Substance ID
141824995, 178102199, 224212434, 230818194, 248997349
Target and Pathway
Target(s) G-protein coupled receptor 55 Target Info Agonist [531335]
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 540939(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5561).
Ref 531335Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity glycine transporter subtype 1 inhibitor and GPR55 agonist. J Pharmacol Exp Ther. 2011 Apr;337(1):236-46.

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