Drug Information

Drug General Information
Drug ID
D0PX7X
Former ID
DIB007086
Drug Name
Re-188-P-2045
Synonyms
Neotide; P-2045; RE-P2045; Rhenium 188-P-2045; Rhenium-188-labeled peptide (lung cancer), Antisoma; Rhenium-188-labeled peptide (lung cancer), Bryan Oncor/ Antisoma
Indication Lung cancer [ICD9: 162; ICD10:C33-C34] Phase 1/2 [533014]
Company
Diatide Inc
Target and Pathway
Target(s) Somatostatin receptor type 2 Target Info Modulator [533014]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways SIDS Susceptibility Pathways
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 533014The somatostatin analog 188Re-P2045 inhibits the growth of AR42J pancreatic tumor xenografts. J Nucl Med. 2014 Dec;55(12):2020-5.
Ref 533014The somatostatin analog 188Re-P2045 inhibits the growth of AR42J pancreatic tumor xenografts. J Nucl Med. 2014 Dec;55(12):2020-5.

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