Drug Information

Drug General Information
Drug ID
D0PJ3M
Former ID
DIB019141
Drug Name
cinnamaldehyde
Synonyms
cinnamic aldehyde
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539553]
Formula
C9H8O
InChI
InChI=1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+
InChIKey
KJPRLNWUNMBNBZ-QPJJXVBHSA-N
PubChem Compound ID
637511
PubChem Substance ID
2237, 4158, 80410, 95576, 587826, 640059, 3132509, 8144663, 8704372, 10508075, 11528262, 12015677, 12075430, 15194529, 17389103, 17389104, 24854395, 24893018, 24900953, 24900954, 29203961, 29215112, 43759822, 48413467, 48417102, 48420325, 48423145, 48424200, 48424973, 48424974, 49855018, 53790538, 56458797, 57407611, 58034048, 80213196, 85272553, 87565485, 88519202, 91234569, 92297864, 93620285, 96026575, 99222912, 102851519, 103131879, 103239041, 104082419, 104667594, 111678075
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily V member 3 Target Info Activator [528302]
Transient receptor potential cation channel subfamily A member 1 Target Info Activator [527012]
KEGG Pathway Inflammatory mediator regulation of TRP channelshsa04750:Inflammatory mediator regulation of TRP channels
Reactome TRP channelsR-HSA-3295583:TRP channels
References
Ref 539553(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2423).
Ref 527012Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron. 2004 Mar 25;41(6):849-57.
Ref 528302More than cool: promiscuous relationships of menthol and other sensory compounds. Mol Cell Neurosci. 2006 Aug;32(4):335-43. Epub 2006 Jul 7.

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