Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0P9AC
|
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| Former ID |
DAP000578
|
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| Drug Name |
Phenelzine
|
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| Synonyms |
Fenelzina; Fenelzyna; Fenelzyne; Phenelezine; Phenelzinum; Phenethylhydrazine; Phenylethylhydrazine; Fenelzyna [Polish]; Fenelzyne [Polish]; W1544; Beta-Phenylethylhydrazine; Fenelzina [INN-Spanish]; Nardelzine (TN); Nardil (TN); Phenelzine (BAN); Phenelzine [INN:BAN]; Phenelzinum [INN-Latin]; Phenylethyl hydrazine-HCl; W 1544-A; 1-Hydrazino-2-phenylethane; 2-Phenethylhydrazine; 2-Phenylethylhydrazine
|
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| Drug Type |
Small molecular drug
|
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| Therapeutic Class |
Antidepressants
|
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| Company |
Parke Davis Div Warner Lambert Co
|
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| Formula |
C8H12N2
|
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| InChI |
InChI=1S/C8H12N2/c9-10-7-6-8-4-2-1-3-5-8/h1-5,10H,6-7,9H2
|
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| InChIKey |
RMUCZJUITONUFY-UHFFFAOYSA-N
|
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| CAS Number |
CAS 51-71-8
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
9634, 5152742, 8152321, 10524963, 11111653, 11111654, 11335237, 11360476, 11363745, 11364679, 11366307, 11367241, 11368869, 11369803, 11371693, 11372844, 11374089, 11375403, 11377031, 11377966, 11461448, 11466198, 11467318, 11484873, 11485696, 11488825, 11490493, 11492290, 11494665, 15297289, 29222798, 46507348, 47291290, 47365378, 47440429, 47440430, 47515488, 47589153, 47589154, 47662481, 47885575, 48334681, 49698876, 49977970, 50111200, 53787015, 57321933, 74503885, 85789353, 90341694
|
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| SuperDrug ATC ID |
N06AF03
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| SuperDrug CAS ID |
cas=000051718
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| Target and Pathway | |||||
| Target(s) | Amine oxidase [flavin-containing] B | Target Info | Inhibitor | [536743] | |
| KEGG Pathway | Glycine, serine and threonine metabolism | ||||
| Arginine and proline metabolism | |||||
| Histidine metabolism | |||||
| Tyrosine metabolism | |||||
| Phenylalanine metabolism | |||||
| Tryptophan metabolism | |||||
| Drug metabolism - cytochrome P450 | |||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Dopaminergic synapse | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Alcoholism | |||||
| Pathway Interaction Database | Alpha-synuclein signaling | ||||
| References | |||||
| Ref 538452 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 011909. | ||||
| Ref 542285 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7266). | ||||
| Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
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