Drug Information

Drug General Information
Drug ID
D0P6VV
Former ID
DAP001100
Drug Name
Dezocine
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Approved [536361]
Therapeutic Class
Analgesics
Formula
C16H23NO
Canonical SMILES
CC12CCCCCC(C1N)CC3=C2C=C(C=C3)O
InChIKey
VTMVHDZWSFQSQP-APHBMKBZSA-N
CAS Number
CAS 53648-55-8
PubChem Compound ID
6337211
PubChem Substance ID
56223384, 57366370, 134338347, 137005169, 225144371, 227587612, 242969056
SuperDrug ATC ID
N02AX03
SuperDrug CAS ID
cas=053648558
Target and Pathway
Target(s) Kappa-type opioid receptor Target Info Antagonist [536176]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Opioid prodynorphin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 536176Pharmacological profiles of opioid ligands at kappa opioid receptors. BMC Pharmacol. 2006 Jan 25;6:3.

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