Drug Information

Drug General Information
Drug ID
D0P0ZB
Former ID
DIB019847
Drug Name
F3
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539529]
Formula
C4H4ClF3
InChI
InChI=1S/C4H4ClF3/c5-3(6)1-2-4(3,7)8/h1-2H2
InChIKey
ZZQYDYODFHABLC-UHFFFAOYSA-N
PubChem Compound ID
79091
PubChem Substance ID
3159885, 5604971, 8200195, 10532046, 15264959, 29328596, 43134617, 57332785, 74793006, 88816095, 95691051, 103099091, 104371818, 117506238, 125373148, 128715433, 129978166, 131498068, 132513227, 134380831, 135034035, 135579092, 135650249, 143455208, 160970324, 162891915, 164792735, 184574960, 229168479, 241116693, 252326469, 252502944, 252502951
Target and Pathway
Target(s) Kir3.2 Target Info Inhibitor (gating inhibitor) [526110]
References
Ref 539529(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2400).
Ref 526110Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels. Anesthesiology. 2001 Jul;95(1):144-53.

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