Drug Information

Drug General Information
Drug ID
D0OR2S
Former ID
DIB005644
Drug Name
Broxaterol
Synonyms
Summair; Z-1170
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Discontinued in Phase 3 [544547]
Company
Zambon Co SpA
Formula
C9H15BrN2O2
Canonical SMILES
c1(cc(no1)Br)C(CNC(C)(C)C)O
CAS Number
CAS 76596-57-1
PubChem Compound ID
71149
Target and Pathway
Target(s) Beta-2 adrenergic receptor Target Info Modulator [533154]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretion
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta2 adrenergic receptor signaling pathway
Pathway Interaction Database Arf6 trafficking events
Arf6 signaling events
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Vitamin D Receptor Pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 544547Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000105)
Ref 533154Broxaterol, a new beta 2-adrenoceptor agonist compared to salbutamol in asthmatics, oral and inhalation treatment. Respiration. 1989;55 Suppl 2:15-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.