Drug Information

Drug General Information
Drug ID
D0OM5M
Former ID
DIB006060
Drug Name
Ro-48-1220
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Terminated [545783]
Company
Roche Holding AG
Canonical SMILES
S1(=O)(=O)[C@]([C@@H](N2[C@H]1CC2=O)C(=O)O)(/C=C\C#N)C
CAS Number
CAS 180323-80-2
Target and Pathway
Target(s) Beta-lactamase Target Info Modulator [526280]
References
Ref 545783Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004684)
Ref 526280Comparative in vitro activity of apalcillin alone and combined with Ro 48-1220, a novel penam beta-lactamase inhibitor. Clin Microbiol Infect. 1995 Feb;1(2):86-100.

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