Drug Information

Drug General Information
Drug ID
D0O4JU
Former ID
DNC011087
Drug Name
(S)-FTY720P
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530125]
Formula
C18H32NO5P
Canonical SMILES
CCCCCCCCC1=CC=C(C=C1)CC(CO)(COP(=O)(O)O)N
InChI
1S/C18H32NO5P/c1-2-3-4-5-6-7-8-16-9-11-17(12-10-16)13-18(19,14-20)15-24-25(21,22)23/h9-12,20H,2-8,13-15,19H2,1H3,(H2,21,22,23)/t18-/m0/s1
InChIKey
RASFIZFJJXYQFE-SFHVURJKSA-N
PubChem Compound ID
25220888
Target and Pathway
Target(s) Sphingosine 1-phosphate receptor 1 Target Info Inhibitor [530125]
KEGG Pathway FoxO signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
IL2 Signaling Pathway
Pathway Interaction Database Fc-epsilon receptor I signaling in mast cells
S1P3 pathway
S1P1 pathway
Sphingosine 1-phosphate (S1P) pathway
PDGFR-beta signaling pathway
Reactome G alpha (i) signalling events
Lysosphingolipid and LPA receptors
WikiPathways Signal Transduction of S1P Receptor
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 530125Nat Chem Biol. 2009 Jun;5(6):428-34.Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.
Ref 530125Nat Chem Biol. 2009 Jun;5(6):428-34.Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.

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