Drug Information

Drug General Information
Drug ID
D0O1HL
Former ID
DIB011930
Drug Name
SC-49483
Drug Type
Small molecular drug
Indication Acquired immune deficiency syndrome [ICD9: 42; ICD10:B20] Phase 2 [521416]
Company
GD Searle & Co
Formula
C26H45NO8
Canonical SMILES
[C@@H]1([C@@H]([C@H](CN([C@@H]1COC(=O)CCC)CCCC)OC(=O)CC<br />C)OC(=O)CCC)OC(=O)CCC
CAS Number
CAS 131262-82-3
PubChem Compound ID
60807
Target and Pathway
Target(s) Maltase-glucoamylase, intestinal Target Info Inhibitor [534275]
KEGG Pathway Galactose metabolism
Starch and sucrose metabolism
Metabolic pathways
Carbohydrate digestion and absorption
PathWhiz Pathway Starch and Sucrose Metabolism
WikiPathways Metabolism of carbohydrates
References
Ref 521416ClinicalTrials.gov (NCT00000791) A Phase II Double-Blind Study of Two Doses of SC-49483 in Combination With Zidovudine (ZDV) Versus ZDV. U.S. National Institutes of Health.
Ref 534275Pathology of perbutylated-N-butyl-1-deoxynojiromycin (an alpha-glucosidase-1 inhibitor) in Sprague-Dawley rats. Toxicol Pathol. 1996 Sep-Oct;24(5):531-8.

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