Drug Information

Drug General Information
Drug ID
D0NA8U
Former ID
DIB000877
Drug Name
Dexamethasone sodium phosphate
Synonyms
EryDex; Dexamethasone sodium phosphate (erythrocyte encapsulated); Dexamethasone sodium phosphate (erythrocyte encapsulated), Urbino University/EryDel; Dex 21-P (red blood cell encapsulated), Urbino University/EryDel; Intra-erythrocyte dexamethasone (inflammatory diseases), Urbino University/EryDel
Drug Type
Small molecular drug
Indication Ataxia telangiectasia [ICD10:G11.3] Approved [549193]
Company
Universita' Degli Studi Di Urbino
Formula
C22H28FNa2O8P
Canonical SMILES
[O-]P(=O)([O-])OCC(=O)[C@@]1([C@@]2([C@H]([C@H]3[C@@]([<br />C@@]4(C(=CC(=O)C=C4)CC3)C)([C@H](C2)O)F)C[C@H]1C)C)O.[N<br />a+].[Na+]
PubChem Compound ID
45357793
Target and Pathway
Target(s) Glucocorticoid receptor Target Info Agonist [532454]
KEGG Pathway Neuroactive ligand-receptor interaction
NetPath Pathway IL2 Signaling Pathway
TCR Signaling Pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
Signaling events mediated by HDAC Class II
FOXA2 and FOXA3 transcription factor networks
Glucocorticoid receptor regulatory network
Regulation of Androgen receptor activity
AP-1 transcription factor network
Reactome BMAL1:CLOCK,NPAS2 activates circadian gene expression
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
SIDS Susceptibility Pathways
Nuclear Receptors Meta-Pathway
Endoderm Differentiation
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Adipogenesis
Circadian Clock
Nuclear Receptors
References
Ref 549193Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033526)
Ref 532454Dexamethasone rapidly increases GABA release in the dorsal motor nucleus of the vagus via retrograde messenger-mediated enhancement of TRPV1 activity. PLoS One. 2013 Jul 30;8(7):e70505.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.