Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N8MQ
|
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| Former ID |
DCL000822
|
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| Drug Name |
GSK-159797
|
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| Synonyms |
Milveterol hydrochloride; Milveterol hydrochloride (USAN); TD-3327
|
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| Drug Type |
Small molecular drug
|
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| Indication | Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47] | Discontinued in Phase 2 | [536223] | ||
| Company |
GlaxoSmithKline
|
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| Formula |
C25H30ClN3O4
|
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| Canonical SMILES |
C1=CC=C(C=C1)C(CNC2=CC=C(C=C2)CCNCC(C3=CC(=C(C=C3)O)NC=<br />O)O)O.Cl
|
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| InChI |
1S/C25H29N3O4.ClH/c29-17-28-22-14-20(8-11-23(22)30)24(31)15-26-13-12-18-6-9-21(10-7-18)27-16-25(32)19-4-2-1-3-5-19;/h1-11,14,17,24-27,30-32H,12-13,15-16H2,(H,28,29);1H/t24-,25-;/m0./s1
|
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| InChIKey |
QQPHRRSYJMOQOC-DKIIUIKKSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Beta-2 adrenergic receptor | Target Info | Agonist | [536223] | |
| NetPath Pathway | TCR Signaling Pathway | ||||
| Pathway Interaction Database | Arf6 trafficking events | ||||
| Arf6 signaling events | |||||
| References | |||||
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