TTD | Drug: D0MR1B

Drug General Information
Drug ID	D0MR1B
Former ID	DIB018889
Drug Name	AS604872
Synonyms	AS 604872; AS-604872
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540367]
Formula	C28H25N3O3S2
InChI	InChI=1S/C28H25N3O3S2/c32-27(30-26(23-11-5-2-6-12-23)25-13-7-8-18-29-25)28-31(19-20-35-28)36(33,34)24-16-14-22(15-17-24)21-9-3-1-4-10-21/h1-18,26,28H,19-20H2,(H,30,32)/t26-,28+/m1/s1
InChIKey	LSSZZFZFFKZTCL-IAPPQJPRSA-N
PubChem Compound ID	10152528
PubChem Substance ID	15144638, 22552070, 40136703, 79160333, 142868847, 178100429, 223970043, 229403625, 243420038
Target and Pathway
Target(s)	Prostaglandin F2-alpha receptor	Target Info	Antagonist	[528941]
KEGG Pathway	Calcium signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Prostanoid ligand receptors
Reactome	G alpha (q) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 540367	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3424).
Ref 528941	Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP). Am J Obstet Gynecol. 2007 Jul;197(1):54.e1-9.

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Drug Information