Drug Information

Drug General Information
Drug ID
D0M7PU
Former ID
DNCL002610
Drug Name
PM-00104
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 2 [522662]
Company
PharmaMar
Formula
C37H38F3N3O8
PubChem Compound ID
16061448
Target and Pathway
Target(s) Human DNA Target Info Modulator [531367]
References
Ref 522662ClinicalTrials.gov (NCT00900562) Clinical Trial of PM00104 (Zalypsis) in Patients With Advanced and/or Metastatic Endometrial or Cervical Cancer Previously Treated With One Line of Systemic Chemotherapy. U.S. National Institutes of Health.
Ref 531367Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response. Haematologica. 2011 May;96(5):687-95.

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