Drug Information

Drug General Information
Drug ID
D0M7NA
Former ID
DCL000026
Drug Name
A-993610
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Investigative [531236]
Therapeutic Class
Analgesics
Company
Abbott
Target and Pathway
Target(s) Vanilloid receptor 1 Target Info Blocker [537396]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channels
References
Ref 531236TRPV1 receptor blockade is ineffective in different in vivo models of migraine. Cephalalgia. 2011 Jan;31(2):172-80.
Ref 537396Analgesic potential of TRPV1 antagonists. Biochem Pharmacol. 2009 Aug 1;78(3):211-6. Epub 2009 Mar 5.

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