Drug Information

Drug General Information
Drug ID
D0M6RM
Former ID
DNC005133
Drug Name
Phenylarsonic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527260]
Formula
C6H7AsO3
Canonical SMILES
C1=CC=C(C=C1)[As](=O)(O)O
InChI
1S/C6H7AsO3/c8-7(9,10)6-4-2-1-3-5-6/h1-5H,(H2,8,9,10)
InChIKey
LVKZSFMYNWRPJX-UHFFFAOYSA-N
PubChem Compound ID
7365
Target and Pathway
Target(s) Carbonic anhydrase IV Target Info Inhibitor [527260]
Carbonic anhydrase Target Info Inhibitor [528141]
KEGG Pathway Nitrogen metabolism
Proximal tubule bicarbonate reclamation
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Reversible hydration of carbon dioxide
WikiPathways Reversible Hydration of Carbon Dioxide
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 527260Bioorg Med Chem Lett. 2004 Dec 6;14(23):5769-73.Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions.
Ref 527260Bioorg Med Chem Lett. 2004 Dec 6;14(23):5769-73.Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions.
Ref 528141Bioorg Med Chem Lett. 2006 Jun 15;16(12):3139-43. Epub 2006 Apr 18.Carbonic anhydrase inhibitors: inhibition of the cytosolic human isozyme VII with anions.

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