Drug Information

Drug General Information
Drug ID
D0LJ4Q
Former ID
DNC005104
Drug Name
8-Propoxy-quinolin-2-ylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527194]
Formula
C12H14N2O
Canonical SMILES
CCCOC1=CC=CC2=C1N=C(C=C2)N
InChI
1S/C12H14N2O/c1-2-8-15-10-5-3-4-9-6-7-11(13)14-12(9)10/h3-7H,2,8H2,1H3,(H2,13,14)
InChIKey
SZBXIIUHFFFWME-UHFFFAOYSA-N
PubChem Compound ID
10420382
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [527194]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.

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