Drug Information

Drug General Information
Drug ID
D0K8AU
Former ID
DNC014365
Drug Name
2-morpholino-N-phenethylpyrimidin-4-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530923]
Formula
C16H20N4O
Canonical SMILES
C1COCCN1C2=NC=CC(=N2)NCCC3=CC=CC=C3
InChI
1S/C16H20N4O/c1-2-4-14(5-3-1)6-8-17-15-7-9-18-16(19-15)20-10-12-21-13-11-20/h1-5,7,9H,6,8,10-13H2,(H,17,18,19)
InChIKey
QCZVHPUPIBZBLH-UHFFFAOYSA-N
PubChem Compound ID
46891060
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [530923]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 530923Bioorg Med Chem Lett. 2010 Jun 15;20(12):3606-9. Epub 2010 Apr 28.Design, synthesis and evaluation of 2,4-disubstituted pyrimidines as cholinesterase inhibitors.
Ref 530923Bioorg Med Chem Lett. 2010 Jun 15;20(12):3606-9. Epub 2010 Apr 28.Design, synthesis and evaluation of 2,4-disubstituted pyrimidines as cholinesterase inhibitors.

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