Drug Information

Drug General Information
Drug ID
D0K5JA
Former ID
DNC005095
Drug Name
8-Cyclohexyloxy-quinolin-2-ylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527194]
Formula
C15H18N2O
Canonical SMILES
C1CCC(CC1)OC2=CC=CC3=C2N=C(C=C3)N
InChI
1S/C15H18N2O/c16-14-10-9-11-5-4-8-13(15(11)17-14)18-12-6-2-1-3-7-12/h4-5,8-10,12H,1-3,6-7H2,(H2,16,17)
InChIKey
MPHNEJNPZMBSBN-UHFFFAOYSA-N
PubChem Compound ID
10399494
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [527194]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.

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