Drug Information

Drug General Information
Drug ID
D0K1HD
Former ID
DIB021116
Drug Name
UCM 793
Synonyms
UCM-793; UCM793
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542729]
Formula
C12H18N2O2
InChI
InChI=1S/C12H18N2O2/c1-10(15)13-7-8-14(2)11-5-4-6-12(9-11)16-3/h4-6,9H,7-8H2,1-3H3,(H,13,15)
InChIKey
FAWOXVGCBAVSFR-UHFFFAOYSA-N
PubChem Compound ID
24750192
PubChem Substance ID
49652377, 56165587, 103541947, 223366110, 229419415, 244566446
Target and Pathway
Target(s) Melatonin receptor Target Info Agonist [529190]
KEGG Pathway Neuroactive ligand-receptor interaction
Circadian entrainment
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 542729(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7777).
Ref 529190N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands. J Med Chem. 2007 Dec 27;50(26):6618-26. Epub 2007 Dec 6.

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