Drug Information

Drug General Information
Drug ID
D0J7NR
Former ID
DNC004192
Drug Name
5-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528087]
Formula
C11H9N3O
Canonical SMILES
CC1=CC=CC2=CC3=C(NC(=O)N3)N=C12
InChI
1S/C11H9N3O/c1-6-3-2-4-7-5-8-10(13-9(6)7)14-11(15)12-8/h2-5H,1H3,(H2,12,13,14,15)
InChIKey
YZNZOJPHYDBVIZ-UHFFFAOYSA-N
PubChem Compound ID
15065143
Target and Pathway
Target(s) CGMP-inhibited 3',5'-cyclic phosphodiesterase A Target Info Inhibitor [528087]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
cAMP signaling pathway
Morphine addiction
Reactome cGMP effects
G alpha (s) signalling events
WikiPathways miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 528087J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.
Ref 528087J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.

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