Drug Information

Drug General Information
Drug ID
D0J3VV
Former ID
DIB000732
Drug Name
IPH-3201
Synonyms
IPH-32XX; TLR-7 modulators (cancer), Cancer Research Technology; TLR-7 modulators (cancer), Innate; Toll-like receptor 7 modulators (cancer), Innate
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Terminated [548555]
Company
Cancer Research Technology Ltd
Target and Pathway
Target(s) Toll-like receptor 7 Target Info Modulator [543475]
KEGG Pathway Toll-like receptor signaling pathway
Measles
Influenza A
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Toll receptor signaling pathway
Reactome Trafficking and processing of endosomal TLR
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
MyD88 dependent cascade initiated on endosome
WikiPathways Toll-like receptor signaling pathway
Toll-Like Receptors Cascades
MyD88 dependent cascade initiated on endosome
Trafficking and processing of endosomal TLR
Regulation of toll-like receptor signaling pathway
References
Ref 548555Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026574)
Ref 543475(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1757).

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