Drug Information

Drug General Information
Drug ID
D0IB8N
Former ID
DNC001034
Drug Name
Noradrenalone (arterenone)
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535831]
Formula
C8H9NO3
Canonical SMILES
C1=CC(=C(C=C1C(=O)CN)O)O
InChI
1S/C8H9NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,10-11H,4,9H2
InChIKey
CNFQARFTXUBHJY-UHFFFAOYSA-N
CAS Number
CAS 51-41-2
PubChem Compound ID
10359
PubChem Substance ID
219188, 5455497, 8157477, 29228863, 49863333, 57326158, 77706762, 103114947, 104323081, 117562120, 125684122, 127649776, 132557651, 134977782, 138836816, 162860154, 172876736, 196384250, 227886773
ChEBI ID
ChEBI:18357
Target and Pathway
Target(s) Aromatic-L-amino-acid decarboxylase Target Info Activator [535831]
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation via tryptamine
Serotonin and melatonin biosynthesis
Catecholamine biosynthesis
KEGG Pathway Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Metabolic pathways
Serotonergic synapse
Dopaminergic synapse
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
5-Hydroxytryptamine biosynthesis
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
PathWhiz Pathway Catecholamine Biosynthesis
Tyrosine Metabolism
Tryptophan Metabolism
WikiPathways SIDS Susceptibility Pathways
Biogenic Amine Synthesis
Tryptophan metabolism
Dopaminergic Neurogenesis
Metabolism of amino acids and derivatives
Dopamine metabolism
Parkinsons Disease Pathway
Nicotine Activity on Dopaminergic Neurons
References
Ref 535831Activation of an adrenergic pro-drug through sequential stereoselective action of tandem target enzymes. Biochem Biophys Res Commun. 1992 Nov 30;189(1):33-9.
Ref 535831Activation of an adrenergic pro-drug through sequential stereoselective action of tandem target enzymes. Biochem Biophys Res Commun. 1992 Nov 30;189(1):33-9.

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