Drug Information

Drug General Information
Drug ID
D0I3TD
Former ID
DIB016025
Drug Name
CRL-37212
Synonyms
Anaplastic lymphoma kinase inhibitors (cancer); CRL-37212; CRL-43425; CRL-82007; ALK inihibitors (cancer), ChemBridge Research; Anaplastic lymphoma kinase inhibitors (cancer), ChemBridge Research
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [543509]
Company
ChemBridge Research Laboratories LLC
Canonical SMILES
c1c(ccc2c1OCO2)c1c[nH]c(=O)c(c1)C(=O)Nc1ccc(cc1)CCN1CCN<br />(CC1)C
Target and Pathway
Target(s) ALK tyrosine kinase receptor Target Info Inhibitor [543509]
KEGG Pathway Non-small cell lung cancer
WikiPathways Differentiation Pathway
References
Ref 543509(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1839).
Ref 543509(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1839).

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