Drug Information

Drug General Information
Drug ID
D0I0UW
Former ID
DNC010155
Drug Name
1-(4-p-Tolyl-butyl)-piperidine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530299]
Formula
C16H25N
Canonical SMILES
CC1=CC=C(C=C1)CCCCN2CCCCC2
InChI
1S/C16H25N/c1-15-8-10-16(11-9-15)7-3-6-14-17-12-4-2-5-13-17/h8-11H,2-7,12-14H2,1H3
InChIKey
ZJZNOPQUDXUEDU-UHFFFAOYSA-N
PubChem Compound ID
45485498
Target and Pathway
Target(s) Histamine H1 receptor Target Info Inhibitor [530299]
Potassium voltage-gated channel subfamily H member 2 Target Info Inhibitor [530299]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
PathWhiz Pathway Muscle/Heart Contraction
Reactome Histamine receptors
G alpha (q) signalling eventsR-HSA-1296072:Voltage gated Potassium channels
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signalingWP706:SIDS Susceptibility Pathways
Hematopoietic Stem Cell Differentiation
Potassium Channels
References
Ref 530299Bioorg Med Chem Lett. 2009 Sep 1;19(17):5043-7. Epub 2009 Aug 5.Structural determinants for histamine H(1) affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs.
Ref 530299Bioorg Med Chem Lett. 2009 Sep 1;19(17):5043-7. Epub 2009 Aug 5.Structural determinants for histamine H(1) affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.