Drug Information

Drug General Information
Drug ID
D0HL1X
Former ID
DIB014878
Drug Name
ISIS-PKK
Synonyms
ISIS-PKKRx; ISIS-TTR Rx
Drug Type
Antisense drug
Indication Amyloid polyneuropathy Phase 3 [549250]
Target and Pathway
Target(s) mRNA of Plasma kallikrein Target Info [551948]
KEGG Pathway Complement and coagulation cascades
NetPath Pathway AndrogenReceptor Signaling Pathway
PANTHER Pathway Blood coagulation
PathWhiz Pathway Coagulation
Reactome Intrinsic Pathway of Fibrin Clot Formation
Activation of Matrix Metalloproteinases
WikiPathways Complement and Coagulation Cascades
Human Complement System
Blood Clotting Cascade
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 549250Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034193)
Ref 551948Clinical pipeline report, company report or official report of ISIS Pharmaceuticals.

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