Drug Information

Drug General Information
Drug ID
D0H8CC
Former ID
DNC005307
Drug Name
Tert-butyl (2S)-1-cyanopyrrolidine-2-carboxylate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527556]
Formula
C10H16N2O2
Canonical SMILES
CC(C)(C)OC(=O)C1CCCN1C#N
InChI
1S/C10H16N2O2/c1-10(2,3)14-9(13)8-5-4-6-12(8)7-11/h8H,4-6H2,1-3H3
InChIKey
BFXLWVDZNFZGJO-UHFFFAOYSA-N
PubChem Compound ID
44398742
Target and Pathway
Target(s) Cathepsin K Target Info Inhibitor [527556]
KEGG Pathway Lysosome
Osteoclast differentiation
Toll-like receptor signaling pathway
Rheumatoid arthritis
NetPath Pathway TGF_beta_Receptor Signaling Pathway
RANKL Signaling Pathway
IL2 Signaling Pathway
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Trafficking and processing of endosomal TLR
MHC class II antigen presentation
WikiPathways RANKL/RANK Signaling Pathway
Osteoclast Signaling
References
Ref 527556Bioorg Med Chem Lett. 2005 Jun 15;15(12):3039-43.Acyclic cyanamide-based inhibitors of cathepsin K.
Ref 527556Bioorg Med Chem Lett. 2005 Jun 15;15(12):3039-43.Acyclic cyanamide-based inhibitors of cathepsin K.

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