Drug Information

Drug General Information
Drug ID
D0G8XL
Former ID
DNC011949
Drug Name
1-(3-Cyano-phenyl)-1H-pyrazole-4-carboxylic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526021]
Formula
C11H7N3O2
Canonical SMILES
C1=CC(=CC(=C1)N2C=C(C=N2)C(=O)O)C#N
InChI
1S/C11H7N3O2/c12-5-8-2-1-3-10(4-8)14-7-9(6-13-14)11(15)16/h1-4,6-7H,(H,15,16)
InChIKey
FFNALGQEMPFZAF-UHFFFAOYSA-N
PubChem Compound ID
43542927
Target and Pathway
Target(s) Xanthine dehydrogenase/oxidase Target Info Inhibitor [526021]
BioCyc Pathway Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Guanosine nucleotides degradation
Adenosine nucleotides degradation
Retinoate biosynthesis II
KEGG Pathway Purine metabolism
Caffeine metabolism
Drug metabolism - other enzymes
Metabolic pathways
Peroxisome
PANTHER Pathway Adenine and hypoxanthine salvage pathway
Purine metabolism
PathWhiz Pathway Caffeine Metabolism
Purine Metabolism
Reactome Purine catabolism
WikiPathways Oxidative Stress
Effects of Nitric Oxide
Metabolism of nucleotides
Selenium Micronutrient Network
References
Ref 526021Bioorg Med Chem Lett. 2001 Apr 9;11(7):879-82.Synthesis and structure-activity relationships of 1-phenylpyrazoles as xanthine oxidase inhibitors.
Ref 526021Bioorg Med Chem Lett. 2001 Apr 9;11(7):879-82.Synthesis and structure-activity relationships of 1-phenylpyrazoles as xanthine oxidase inhibitors.

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