Drug Information

Drug General Information
Drug ID
D0G7QT
Former ID
DIB019813
Drug Name
EMD-386088
Synonyms
compound 18 [PMID 16055331]; EMD 386088; EMD386088
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527665]
Formula
C14H15ClN2
InChI
InChI=1S/C14H15ClN2/c1-9-14(10-4-6-16-7-5-10)12-8-11(15)2-3-13(12)17-9/h2-4,8,16-17H,5-7H2,1H3
InChIKey
BPPGPYJBCVXILI-UHFFFAOYSA-N
PubChem Compound ID
10131112
PubChem Substance ID
15122103, 22533834, 26755027, 39969542, 57374260, 75266803, 85787653, 103468750, 104057488, 125647002, 127549853, 131318397, 140775887, 144087476, 162221563, 218009262, 227746914, 252166638
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Agonist [527665]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 527665Bioorg Med Chem Lett. 2005 Oct 1;15(19):4230-4.2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.
Ref 527665Bioorg Med Chem Lett. 2005 Oct 1;15(19):4230-4.2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.

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