Drug Information

Drug General Information
Drug ID
D0G4YR
Former ID
DIB005294
Drug Name
MT-3995
Indication Diabetic nephropathy [ICD9: 250.4; ICD10:E11.21] Phase 2 [524170]
Company
Mitsubishi tanabe pharma
Target and Pathway
Target(s) Mineralocorticoid receptor Target Info Antagonist [533270]
KEGG Pathway Aldosterone-regulated sodium reabsorption
PathWhiz Pathway Kidney Function
WikiPathways ACE Inhibitor Pathway
References
Ref 524170ClinicalTrials.gov (NCT01756703) A Study to Evaluate Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of MT-3995 in Type II Diabetic Nephropathy Subjects With Albuminuria. U.S. National Institutes of Health.
Ref 533270Nonsteroidal antagonists of the mineralocorticoid receptor. Curr Opin Nephrol Hypertens. 2015 Sep;24(5):417-24.

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