Drug Information

Drug General Information
Drug ID
D0G4ES
Former ID
DIB009092
Drug Name
Tetrandrine
Synonyms
Tetrandrine, Millenia Hope; Tetrandrine, West Virginia University; Tranex-18
Drug Type
Small molecular drug
Indication Colorectal cancer [ICD9: 153, 154; ICD10:C18-C21] Discontinued in Phase 3 [548123]
Company
West Virginia University
Formula
C38H42N2O6
Canonical SMILES
c12c3[C@@H](N(CCc3cc(c2OC)OC)C)Cc2cc(Oc3ccc(C[C@H]4c5cc<br />(O1)c(cc5CCN4C)OC)cc3)c(cc2)OC
CAS Number
CAS 518-34-3
PubChem Compound ID
73078
Target and Pathway
Target(s) Calcium channel Target Info Antagonist [529052]
References
Ref 548123Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022136)
Ref 529052Tetrandrine: a novel calcium channel antagonist inhibits type I calcium channels in neuroblastoma cells. Neuropharmacology. 1991 Dec;30(12A):1325-31.

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