Drug Information

Drug General Information
Drug ID
D0FV7K
Former ID
DNC007928
Drug Name
4-((1H-indol-1-yl)methyl)benzenamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528630]
Formula
C15H14N2
Canonical SMILES
C1=CC=C2C(=C1)C=CN2CC3=CC=C(C=C3)N
InChI
1S/C15H14N2/c16-14-7-5-12(6-8-14)11-17-10-9-13-3-1-2-4-15(13)17/h1-10H,11,16H2
InChIKey
CRNJIXJRSKNGTP-UHFFFAOYSA-N
PubChem Compound ID
19779451
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Inhibitor [528630]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 528630Bioorg Med Chem Lett. 2007 Mar 15;17(6):1691-4. Epub 2007 Jan 4.Further studies on the binding of N1-substituted tryptamines at h5-HT6 receptors.
Ref 528630Bioorg Med Chem Lett. 2007 Mar 15;17(6):1691-4. Epub 2007 Jan 4.Further studies on the binding of N1-substituted tryptamines at h5-HT6 receptors.

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