TTD | Drug: D0F4UT

Drug General Information
Drug ID	D0F4UT
Former ID	DNC009964
Drug Name	2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530333]
Formula	C16H16O3S
Canonical SMILES	C1=CC=C(C=C1)C2=CC=C(C=C2)CCS(=O)CC(=O)O
InChI	1S/C16H16O3S/c17-16(18)12-20(19)11-10-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9H,10-12H2,(H,17,18)
InChIKey	JPUWBNMOSGBVRW-UHFFFAOYSA-N
PubChem Compound ID	21496278
Target and Pathway
Target(s)	MMP-12	Target Info	Inhibitor	[530333]
NetPath Pathway	IL1 Signaling Pathway
NetPath Pathway	IL5 Signaling Pathway
Pathway Interaction Database	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome	Collagen degradation
Reactome	Degradation of the extracellular matrix
WikiPathways	TGF beta Signaling Pathway
	Degradation of collagen
	Matrix Metalloproteinases
References
Ref 530333	Bioorg Med Chem Lett. 2009 Oct 1;19(19):5760-3. Epub 2009 Aug 6.The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors.
Ref 530333	Bioorg Med Chem Lett. 2009 Oct 1;19(19):5760-3. Epub 2009 Aug 6.The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors.

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Drug Information