Drug Information

Drug General Information
Drug ID
D0F4LI
Former ID
DIB003014
Drug Name
LASSBio-881
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Investigative [543861]
Company
Universidade Federal do Rio de Janeiro
Formula
C23H27N3O6
Canonical SMILES
c1c(c(cc2c1OCO2)C(=O)N/N=C/c1cc(c(c(c1)C(C)(C)C)O)C(C)(<br />C)C)[N+](=O)[O-]
PubChem Compound ID
16721055
Target and Pathway
Target(s) Vanilloid receptor 1 Target Info Agonist [543861]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channels
References
Ref 543861(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 507).
Ref 543861(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 507).

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