Drug Information

Drug General Information
Drug ID
D0F3KP
Former ID
DNC001432
Drug Name
Thiocarbamate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [537992]
Formula
CH2NOS-
Canonical SMILES
C(=S)(N)[O-]
InChI
1S/CH3NOS/c2-1(3)4/h(H3,2,3,4)/p-1
InChIKey
GNVMUORYQLCPJZ-UHFFFAOYSA-M
PubChem Compound ID
21226412
PubChem Substance ID
37337061, 134340614, 137002112, 223973676
Target and Pathway
Target(s) Squalene monooxygenase Target Info Inhibitor [537992]
KEGG Pathway Steroid biosynthesis
Sesquiterpenoid and triterpenoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Biosynthesis of antibiotics
PathWhiz Pathway Steroid Biosynthesis
Reactome Cholesterol biosynthesis
Activation of gene expression by SREBF (SREBP)
References
Ref 537992Characterization of squalene epoxidase activity from the dermatophyte Trichophyton rubrum and its inhibition by terbinafine and other antimycotic agents. Antimicrob Agents Chemother. 1996 Feb;40(2):443-7.
Ref 537992Characterization of squalene epoxidase activity from the dermatophyte Trichophyton rubrum and its inhibition by terbinafine and other antimycotic agents. Antimicrob Agents Chemother. 1996 Feb;40(2):443-7.

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