Drug Information

Drug General Information
Drug ID
D0EP5O
Former ID
DIB013874
Drug Name
NS-377
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Terminated [545922]
Company
NeuroSearch A/S
Canonical SMILES
c12c(C(=O)C(=O)N2)cc(c2c1CN(C2)CC)c1ccccc1
CAS Number
CAS 160753-45-7
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Antagonist [534702]
References
Ref 545922Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005356)
Ref 534702In vivo and in vitro evaluation of AMPA receptor antagonists in rat hippocampal neurones and cultured mouse cortical neurones. Eur J Pharmacol. 1998 Jul 24;353(2-3):159-67.

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