Drug Information

Drug General Information
Drug ID
D0EA7Z
Former ID
DNC008147
Drug Name
4-propyl-3,4-dihydroquinazolin-2-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529148]
Formula
C11H15N3
Canonical SMILES
CCCC1C2=CC=CC=C2NC(=N1)N
InChI
1S/C11H15N3/c1-2-5-9-8-6-3-4-7-10(8)14-11(12)13-9/h3-4,6-7,9H,2,5H2,1H3,(H3,12,13,14)
InChIKey
GMMVLHFFOQJVPH-UHFFFAOYSA-N
PubChem Compound ID
44455983
Target and Pathway
Target(s) 5-hydroxytryptamine 5A receptor Target Info Inhibitor [529148]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529148Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation.
Ref 529148Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation.

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