Drug Information

Drug General Information
Drug ID
D0E6KN
Former ID
DNCL003589
Drug Name
GSK2647544
Synonyms
GSK-2647544
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Phase 1 [524402]
Company
GlaxoSmithKline
Target and Pathway
Target(s) Lipoprotein-associated phospholipase A2 Target Info Modulator [543419]
KEGG Pathway Ether lipid metabolism
Metabolic pathways
Biosynthesis of antibiotics
Pathway Interaction Database Lissencephaly gene (LIS1) in neuronal migration and development
WikiPathways IL1 and megakaryotyces in obesity
Synthesis, Secretion, and Deacylation of Ghrelin
References
Ref 524402ClinicalTrials.gov (NCT01924858) A Positron Emission Tomography (PET) Study to Investigate the Brain Biodistribution of 18F GSK2647544 in Healthy Subjects to Determine Its Ability to Cross the Blood-brain-barrier.. U.S. National Institutes of Health.
Ref 543419(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1432).

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