Drug Information

Drug General Information
Drug ID
D0E5XM
Former ID
DIB020044
Drug Name
imbutamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538763]
Formula
C7H13N3
InChI
InChI=1S/C7H13N3/c8-4-2-1-3-7-5-9-6-10-7/h5-6H,1-4,8H2,(H,9,10)
InChIKey
VJSUMPPMFYQOMP-UHFFFAOYSA-N
PubChem Compound ID
13499360
PubChem Substance ID
36744360, 49846721, 54020576, 103302059, 125757787, 129485055, 132593487, 135650379, 140071320, 163161033, 224776256, 229862279, 249782272
Target and Pathway
Target(s) Histamine H3 receptor Target Info Agonist [526894]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 538763(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1249).
Ref 526894Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists. J Med Chem. 2003 Dec 4;46(25):5445-57.

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