Drug Information

Drug General Information
Drug ID
D0E3ST
Former ID
DNC007939
Drug Name
1-(4-ethylpiperazin-1-yl)-2-phenylethanone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528722]
Formula
C14H20N2O
Canonical SMILES
CCN1CCN(CC1)C(=O)CC2=CC=CC=C2
InChI
1S/C14H20N2O/c1-2-15-8-10-16(11-9-15)14(17)12-13-6-4-3-5-7-13/h3-7H,2,8-12H2,1H3
InChIKey
ZKLSFAKJJJDQSA-UHFFFAOYSA-N
PubChem Compound ID
3328378
Target and Pathway
Target(s) Corticosteroid 11-beta-dehydrogenase, isozyme 1 Target Info Inhibitor [528722]
KEGG Pathway Steroid hormone biosynthesis
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways
Chemical carcinogenesis
NetPath Pathway IL1 Signaling Pathway
FSH Signaling Pathway
PathWhiz Pathway Steroidogenesis
Reactome Glucocorticoid biosynthesis
WikiPathways Prostaglandin Synthesis and Regulation
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 528722Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. Epub 2007 Feb 25.Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.
Ref 528722Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. Epub 2007 Feb 25.Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.

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